Carla introduces her new boyfriend, Peter, to the group; Craig announces his candidacy for the state Assembly; an affair threatens Craig's political career.
The friends gather at Samantha's grave to pay their respects and reminisce; Samantha cancels plans on her 25th birthday after one of the ER patients she releases suddenly dies.
When the six friends and their dates celebrate Thanksgiving together, ulterior motives, accusations, jealousy and blame plague the dinner.
Sam and Will's daughter is kidnapped, and Sam is forced to tell Craig the truth about her pregnancy; Will returns from the Persian Gulf with a final errand to complete for a friend who was killed in action.
Carla isolates herself by keeping secrets from the new man in her life and from Samantha; Jenna and her mother manage to reconnect before another tragedy strikes.
A wedding brings out old rivalries when Samantha must finally choose between Craig and Will.
The competition between Will and Craig for Samantha escalates, and Will, who now works for Craig's father, goes too far and crosses ethical and legal boundaries.
A former cellmate offers Will a business proposition; Detective Marjorino traces the murder weapon to one of the friends.
Several people reunite at the funeral of a friend; formative events in 1986 alter their dreams and the course of their lives.