A college student is stabbed to death while working the nightshift at a convenience store, and her murder goes unsolved for 10 years until an informant steps forward.
Washington authorities are stunned when a mother of three dies from cyanide poisoning, and their murder investigation uncovers a pattern of tampering with boxes and blister packs.
After the mutilated body of 17-year-old Shauna Card is discovered on the bathroom floor in her Orlando, Fla., home, it will take years for investigators to finally crack the case.
When a 20-year-old woman is gunned down in a Maryland suburb, the case goes cold with few leads and almost no evidence, and it will take 25 years before investigators finally close in on the killer.
In Kilgore, Texas, the residents are reeling from the execution-style slaying of five people abducted from a fast-food restaurant, and it will take several decades before the perpetrators are brought to justice.
A TV celebrity leads a major media campaign after a hardworking single mother is murdered in a Michigan town where violent crimes are nearly four times the national average.
The rape and murder of a 19-year-old journalism student in her bed is the latest in a string of unsolved homicides in a college town.
During a slumber party, a man appears at 12-year-old Polly Klaas's bedroom door and abducts her at knife point.
Three blood-soaked dogs are the only witnesses to the brutal murder of Cathy Lamb in her Palm Beach, Fla., home, leaving detectives baffled by the gruesome crime scene.
Single mother Donna Kitowski heads to a Las Vegas supermarket late at night but never returns home, and soon the local TV news is reporting on a woman's near-lifeless body found in the desert..
Investigators must determine the identity of a murder victim whose skull was found on a highway in Florida.
When a flight attendant goes missing, detectives are baffled until a graveside discovery forces them to take a second look at some familiar faces.
Firefighters in Tempe, Ariz. discover the body of Kathleen Smith inside a flame-licked townhouse. Earlier, witnesses saw a young man fleeing the same home.
John and Nancy Bosco were supposed to be in Colorado. Instead, the sheriff found them decomposing in their Montana home.
The case of 18-year-old Amy Roman, who was murdered in her Boston apartment in May 1990. Though police believed the young mother knew her assailant, the trail went cold, prompting her relatives into launching an investigation of their own. Fifteen years later, an arrest was made
Babysitter Karen Slattery is brutally stabbed and raped while babysitting in Southern Florida's Delray Beach. Case cold until a similar crimes terrorises in nearby Boca Raton.
A Florida couple with a thriving business and a baby on the way is strangled to death in their home; detectives believe drug smuggling played a part in their deaths.
A body is discovered in an apartment fire; police catch the killer with blood found in the kitchen.
After children find body parts in garbage bags, detectives employ a forensic anthropologist and cutting-edge technology in order to solve this grisly murder.
A woman is certain that her husband was wrongly convicted of killing her mother and starts an investigation of her own.
In a tranquil Austin, Texas, neighborhood, a woman shows her high-end home to a killer posing as a prospective buyer.
Detectives discuss their hunt for a murderer, rapist and master of disguises, who dressed up in ladies' clothes in order to get into women's homes.
Investigators reflect on their difficult search for the culprit behind the chilling murder of a 29-year-old woman on Halloween.
September 4, 1980-Thornton, Colorado. Fifteen-year-old Nanine Grimes is found murdered in her home. Despite many promising leads over they years, the case goes ice cold...until 26 years later when a national database of criminal DNA is created.
Sharon Bloom vanishes after leaving work to go out for lunch; her body is discovered 10 days later in a cornfield.
Detectives hunt for the murderer of a 30-year-old mother. However, even when they think they've found their killer, they face a frustrating search for evidence.
Using a novel technique involving a deck of cards, detectives crack a 32-year-old cold case, finally bringing an assassin to justice.
When Nancy Manni's lifeless body is found floating in Chesapeake Bay the Maryland Natural Resources Police catch the case.Detective Dennis Leland worries she got on the wrong boat with the wrong guy.
Family and friends are frantic when 42-year-old Jeanine Harms goes out on a date and disappears into thin air. Her apartment shows no outward signs of a struggle, but a Persian rug is missing. Has Harms' body been rolled up in the rug and dumped?
A Vancouver man is shot on his doorstep; other local murders appear to be connected.
While digging in a dumpster, a homeless man makes the gruesome discovery of a human arm; after a second arm is found at the scene, the hunt is on for a killer - and the rest of the body.
A mother leaves for a weekend and is never seen again; a detective goes undercover to find the killer.
While searching for a missing realtor and his wife, police make a grisly discovery inside the trunk of a car - their bodies; a nationwide hunt for the killer ensues.
A body found in a cement quarry has the signs of a mob hit, but as detectives look into the case, they discover a far stranger truth.
A man's body is found near train tracks and his girlfriend is missing; while searching for the killer and the missing girl, investigators land in the world of freight train riders and serial killers.
After the blood-soaked body of a young woman is found on the floor of her apartment in Orlando, Fla., it's up to investigators to find her killer before he strikes again.
Debra Dill's bludgeoned body is discovered next to her car on a September morning in 1973, and it will take nearly two decades to put her killer behind bars.
Kimberly Dunkin's body is found with a single gunshot wound to the head, and though investigators suspect she was the victim of gang violence, it will take 15 years, a deck of playing cards and a lucky break before the case breaks.
Matthew Monahon returns home to discover his pregnant wife, Kelsey, hogtied on the floor and clinging to life, then she dies a few days later, and a $300,000 life insurance policy surfaces, turning Monahon into the number one suspect.
The dumping of a woman's body prompts detectives to begin connecting the dots and find the link between seemingly random beatings, carjackings and murders.
In Oregon, 19-year-old college student Brooke Wilberger, a devout Mormon, is abducted from a parking lot in broad daylight, prompting a massive search that grabs headlines across the country.
Years after a woman is shot and the case goes cold, news of a potential prison confession leads investigators back to her front door.
On her last day of school, a 14-year-old girl is brutally beaten and set on fire, sending shock waves through her California community.
In Cleveland, a 14-year-old African-American girl is snatched off the street, assaulted and murdered on her way to school, and it will take detectives nearly 30 years to put her killer behind bars.
In Iowa, a pregnant 23-year-old woman is shot in her own bed, and investigators must determine if they are looking for someone with a deadly grudge or a culprit closer to home.
Employees at a security company receive a puzzling call from their boss; they learn that he has been shot and died.