A college student is stabbed to death while working the nightshift at a convenience store, and her murder goes unsolved for 10 years until an informant steps forward.
Washington authorities are stunned when a mother of three dies from cyanide poisoning, and their murder investigation uncovers a pattern of tampering with boxes and blister packs.
After the mutilated body of 17-year-old Shauna Card is discovered on the bathroom floor in her Orlando, Fla., home, it will take years for investigators to finally crack the case.
When a 20-year-old woman is gunned down in a Maryland suburb, the case goes cold with few leads and almost no evidence, and it will take 25 years before investigators finally close in on the killer.
In Kilgore, Texas, the residents are reeling from the execution-style slaying of five people abducted from a fast-food restaurant, and it will take several decades before the perpetrators are brought to justice.
A TV celebrity leads a major media campaign after a hardworking single mother is murdered in a Michigan town where violent crimes are nearly four times the national average.
The rape and murder of a 19-year-old journalism student in her bed is the latest in a string of unsolved homicides in a college town.
During a slumber party, a man appears at 12-year-old Polly Klaas's bedroom door and abducts her at knife point.
Three blood-soaked dogs are the only witnesses to the brutal murder of Cathy Lamb in her Palm Beach, Fla., home, leaving detectives baffled by the gruesome crime scene.
Single mother Donna Kitowski heads to a Las Vegas supermarket late at night but never returns home, and soon the local TV news is reporting on a woman's near-lifeless body found in the desert..
Investigators must determine the identity of a murder victim whose skull was found on a highway in Florida.
Recounting a case surrounding the disappearance of a glamorous flight attendant. A lack of clues left detectives baffled, until a graveside discovery forced them to take a second look at some familiar faces
The case of Kathleen Smith, who was bludgeoned to death and set on fire in her Arizona home in October 1984. Detectives had two suspects, but no hard evidence to tie either of them to the attack. Fifteen years after the 20-year-old's murder, a tip-off from a notorious killer reopened the investigation
The murders of John and Nancy Bosco, shot at close range in their Montana home in August 1993. With few clues, the investigation to find the assassin soon stalled so John's mother eventually turned to an unorthodox source for help
The case of 18-year-old Amy Roman, who was murdered in her Boston apartment in May 1990. Though police believed the young mother knew her assailant, the trail went cold, prompting her relatives into launching an investigation of their own. Fifteen years later, an arrest was made
The murders of Mike MacIvor and his heavily pregnant wife Missy, who were strangled to death in their Florida Keys home in August 1991. Suspicions about drug smuggling and a tip about a business deal gone wrong directed detectives to Belize, but for a while the case made little progress. However, investigators later took a new approach that led them straight to the killer
A body is discovered in an apartment fire; police catch the killer with blood found in the kitchen.
After children find body parts in garbage bags, detectives employ a forensic anthropologist and cutting-edge technology in order to solve this grisly murder.
A woman is certain that her husband was wrongly convicted of killing her mother and starts an investigation of her own.
In a tranquil Austin, Texas, neighborhood, a woman shows her high-end home to a killer posing as a prospective buyer.
Detectives discuss their hunt for a murderer, rapist and master of disguises, who dressed up in ladies' clothes in order to get into women's homes.
The murder of 29-year-old Renee Rondeau, who was found strangled in the bathroom of her Lakeview apartment the day after Halloween in 1994. Three years later, Andre Griggs and Benita Johnson were convicted of the crime
Detectives reveal how DNA evidence led them to 15-year-old Nanine Grimes' killer, a quarter of a century after she was stabbed more than 80 times in her Adams County home in September 1980
Detectives investigate the murder of two women in Minnesota. The evidence points to a serial killer, but they wonder whether the deaths are linked or just a sinister coincidence
Detectives hunt for the murderer of a 30-year-old mother. However, even when they think they've found their killer, they face a frustrating search for evidence.
Using a novel technique involving a deck of cards, detectives crack a 32-year-old cold case, finally bringing an assassin to justice.
Family and friends are frantic when 42-year-old Jeanine Harms goes out on a date and disappears into thin air. Her apartment shows no outward signs of a struggle, but a Persian rug is missing. Has Harms' body been rolled up in the rug and dumped?
A Vancouver man is shot on his doorstep; other local murders appear to be connected.
While digging in a dumpster, a homeless man makes the gruesome discovery of a human arm; after a second arm is found at the scene, the hunt is on for a killer - and the rest of the body.
A mother leaves for a weekend and is never seen again; a detective goes undercover to find the killer.
While searching for a missing realtor and his wife, police make a grisly discovery inside the trunk of a car - their bodies; a nationwide hunt for the killer ensues.
A body found in a cement quarry has the signs of a mob hit, but as detectives look into the case, they discover a far stranger truth.
A man's body is found near train tracks and his girlfriend is missing; while searching for the killer and the missing girl, investigators land in the world of freight train riders and serial killers.
After the blood-soaked body of a young woman is found on the floor of her apartment in Orlando, Fla., it's up to investigators to find her killer before he strikes again.
Debra Dill's bludgeoned body is discovered next to her car on a September morning in 1973, and it will take nearly two decades to put her killer behind bars.
Kimberly Dunkin's body is found with a single gunshot wound to the head, and though investigators suspect she was the victim of gang violence, it will take 15 years, a deck of playing cards and a lucky break before the case breaks.
Matthew Monahon returns home to discover his pregnant wife, Kelsey, hogtied on the floor and clinging to life, then she dies a few days later, and a $300,000 life insurance policy surfaces, turning Monahon into the number one suspect.
The dumping of a woman's body prompts detectives to begin connecting the dots and find the link between seemingly random beatings, carjackings and murders.
In Oregon, 19-year-old college student Brooke Wilberger, a devout Mormon, is abducted from a parking lot in broad daylight, prompting a massive search that grabs headlines across the country.
Years after a woman is shot and the case goes cold, news of a potential prison confession leads investigators back to her front door.
On her last day of school, a 14-year-old girl is brutally beaten and set on fire, sending shock waves through her California community.
In Cleveland, a 14-year-old African-American girl is snatched off the street, assaulted and murdered on her way to school, and it will take detectives nearly 30 years to put her killer behind bars.
In Iowa, a pregnant 23-year-old woman is shot in her own bed, and investigators must determine if they are looking for someone with a deadly grudge or a culprit closer to home.
Employees at a security company receive a puzzling call from their boss; they learn that he has been shot and died.