Dr. Joyner helps an abandoned newborn in need of heart surgery; Kellerman performs surgery alongside an ex-lover; a homeless man is stabbed in the waiting room.
A man who believes he is a space alien refuses surgery; Donge plots to become the chief administrator; Kellerman finds out his ex-wife is pregnant.
Maggie Yang treats a blues singer (Macy Gray) for a career-threatening condition; one patient seems to be able to heal others just by touching them.
On Halloween, Maggie Yang reads about a rash of hospital murders 50 years ago; an administrator and his friend are arrested for fighting with fraternity boys over a parking space.
An executive creates a virtual doctor to save money for the hospital; a death-row prisoner and a private citizen both need the same harvested heart to survive.
Dr. Wiseman risks flying his jet in stormy weather to deliver a heart to a transplant recipient in Las Vegas.
A car mows down people at a bus stop in front of Mission General; Kellerman allows his superstitions to interfere with his performance during open-heart surgery on a Buddhist dignitary.
Intern Maggie Yang copes with the chaos caused by a television camera crew; Kellerman steals a machine to help a heart patient.
Doctors at Mission General Hospital in San Francisco bend the rules and exploit loopholes to treat their patients.