When a pregnant woman is murdered and her unborn baby is taken away, investigators from the state's attorney's office race to find the baby and the killer.
When Antonio and Nagel investigate the supposed suicide of a cancer-riddled Chicago PD officer found in a bathtub, they determine the death was a murder; the murder investigation leads to an old nemesis of Stone's.
A man found stabbed to death in his home is discovered to be a former Navy SEAL who was writing a book that exposed the truth about a top secret mission.
After a prominent judge is shot and killed while leaving a bar with Valdez, the team learns the judge's death is connected to a trial in which he handed down a lenient sentence to a college rapist.
When a Muslim grad student is brutally murdered, Stone and the team arrest his friend, another Muslim student, who claims he committed murder to prevent a terrorist attack.
Stone and the state's attorney team probe the events following the arrest and death of a young man and seek charges against police, the fire department and medical personnel.
Peter Stone, his team, and investigator Dawson try to bring a warehouse arsonist to justice, and the suspect's high-powered attorney tries to get his client acquitted.