A mad judge uses radio signals to control the minds of locals.
Burke is called in to investigate the strange death of an atomic plant officer in a small town where residents have an abnormal fear of strangers.
The United States and Russia collaborate on finding a Soviet agent feared to have been kidnapped by China.
Burke must take action when the deposed king of Egypt begins collecting a secret arsenal of weapons to take over what he has lost.
Burke is sent to Ceylon to investigate a ransom note received by the U.S. government.
Burke's boss has devised an ambitious project called Operation Eyeball.
A warehouse explosion destroys evidence needed to convict an international narcotics king, who has recently begun smuggling missiles into South America.
Exiled South American dictator Pedro Cabrial is living in a Spanish castle but aspires to return to power with the help of foreign financial aid.
Burke heads to London to battle power-crazed tycoon Alexander Szabo, a maniac who possesses a deadly truth serum.
Union Seecorps, a fanatical revolutionary group led by Harrison Quentin Filmore, aims to bring peace to the world through Operation Euphoria, staring with a dose of LSD gas in Washington, D.C.
A special installation in Washington, D.C. is protecting a renowned cryptographer and head clerk of a U.S. Intelligence installation.
Burke is in Mexico City to learn who is behind an assassination attempt against the Mexican government's labor leader.
Burke is sent behind the Iron Curtain to smuggle out a famous scientist who has developed an ultra-powerful nuclear device.
Burke investigates two murders in London, where the victims, a German electronics expert and a Yugoslavian engineer, had one thing in common: they both died after calling a certain number.
Burke poses as a jewel thief and infiltrates a criminal syndicate planning to put New York City to sleep with gas introduced into all the steam mains.
Burke is sent to Paris to locate the missing son of an American diplomat.
Burke turns in his police badge to work as a secret agent for the federal government; in his first assignment, he travels to Switzerland to work with the local police to crack an international ring of gold smugglers.
A greeting card company owner dies during the annual company dinner.
A concert pianist hits the wrong chord during a concert and is blown to bits; guests Martha Hyer, Nehemiah Persoff.
Burke crosses paths with Honey West (Anne Francis) during his investigation of a banker's skid-row murder.
A doctor is murdered, and his sometimes-amnesiac wife is missing; guests John Ireland, Una Merkel, Sal Mineo, Paul Richards.
Burke joins the cast of 'Hamlet' to learn who killed two of the leads; with Eddie Foy Jr., Basil Rathbone.
A novelist refuses to name who tried to kill him; guests Lola Albright, Rory Calhoun, Tom Ewell, Kevin McCarthy.
After his mentor is found shot dead in an alley, Amos finds an envelope addressed to himself in the man's apartment; with Hal March, Ricardo Montalban; Terry Moore; Susan Strasberg; James Whitmore.
In Mexico, authorities accuse Burke of the murders of a magazine reporter and a villager in a boat explosion; guest Theodore Bikel.
A window-dresser finds a body hidden hidden behind the drapes; guests Joan Bennett, Edd Byrnes, Arlene Dahl, Paul Lynde, Bert Parks.
Burke poses as a clown to catch a blackmailer of circus performers; guests Betty Hutton, Terry-Thomas, Jack Weston.
A singing cowboy rides into a rodeo, then falls dead from the saddle; with Barbara Eden, Fernando Lamas, Virginia Mayo.
A stockholder in a cat costume dies during a party at his home; guests Macdonald Carey, Diana Hyland, Martha Raye, Don Rickles.
A newspaper comic strip provides clues to the murder of an amateur tennis champion.
An elderly woman who sold maps of stars' homes is slain; guests Eddie Albert, Hans Conreid, Dennis Day, Sheree North, Russ Tamblyn.
An exploding cigar kills a widely hated toy-manufacturer; guests Joan Caulfield, Martha Hyer, Abbe Lane, Louis Nye, Chill Wills.
A children's author is strangled with her own typewriter ribbon; guests Lola Albright, Ann Blyth, George Hamilton, Walter Pidgeon.
A poison dart, shot from ringside seats, kills a professional wrestler; guests Frankie Avalon, Annette Funicello, Jeanne Crain.
A shipping magnate is found lashed to the anchor of his yacht.
A building contractor is found impaled on a meat hook in his own walk-in refrigerator; guests Dick Clark, Janis Paige, Don Rickles.
At a gathering of detectives, a chief of police is shot and a diamond is stolen; guests Howard Duff, Cesar Romero.
An accused embezzler is found murdered in a hotel room; guests Hans Conreid, Broderick Crawford, Burgess Meredith, Mamie Van Doren.
A magician dies, but not by drowning, in a coffin at the bottom of a pool; guests Nick Adams, Paul Lynde, Jill St. John.
Her sisters and her manager are suspected of killing a singing star; guests Eduardo Ciannelli, Steve Cochran, Juliet Prowse.
At a press interview, a wealthy man's bookkeeper is shot with a long-range rifle; guests George Hamilton, Ricardo Montalban.
A woman is found dead in her pool with a gunshot wound to her midsection, and her relatives become the suspects.
Cornelius Gilbert, the owner of one of the world's largest hotel chains, is electrocuted in his swimming pool by a high-voltage wire.
The body of a coin collector is found in the back room of an auction gallery; guests Nick Adams, Patsy Kelly.
Each victim's wife had a motive in the poisoning of four country-club members; guests Arlene Dahl, June Havoc.
The head of a major modeling agency is slain; guests Vera Miles, Terry Moore, John Saxon, David Wayne.
A publisher is shot while lying on her bed with a facial mask on, and the list of possible murderers is long and distinguished.
Cyanide-laced bourbon fells a vaudevillian; guests Jim Backus, William Demarest, Eddie Foy Jr., Phil Harris, Gypsy Rose Lee.
A rare poison that interacts with seawater kills a surfing actress; guests Theodore Bikel, Macdonald Carey, Dorothy Lamour.
A firm's co-owner is found murdered by an apparent elevator fall.
The probe of a museum murder implicates the victim's partner, mother and a museum guide; with John Cassavetes, Cesar Romero.
A woman is fatally stabbed in a mud bath at a health spa catering to the wealthy; guests Jeanne Crain, Susan Strasberg.
Burke's old flame is slain two hours after she was with him; guests Richard Carlson, Jane Greer, Don Taylor, Ruta Lee.
A baseball player pleads his innocence in the killing of a playgirl; guests Don Ameche, Gena Rowlands, Jackie Coogan.
Foolish investments offer a list of prime suspects in the death of a millionaire.
The death of a housewife in her shower turns out to be murder; guests Hoagy Carmichael, Nanette Fabray, Jayne Mansfield.
A lost shoe provides clues to the murder of an Oriental philosophy professor.
A leading art satirist gets impaled on one of his own paintings in the galleries where he was holding a show.
A peculiar knife and a two-faced key provide clues to the murder of a famous industrial designer.
Just after a dinner party with former and current wives, an agent is stabbed; guests Herschel Bernardi, John Ericson.
A duke gets a lethal dose of belladonna at a dinner party; guests Linda Darnell, Elizabeth Montgomery, Mickey Rooney.
A murdered model was the protege of an oil millionaire; guests Michael Ansara, Jim Backus, Fernando Lamas, Diana Lynn.
A woman, shot twice, is found in a junkyard; guests Hans Conreid, Jack Carter, Martha Hyer, Louis Nye.
A lawyer calls Burke to report his own murder, but dies before naming the culprit; guests Gene Autry, Carolyn Jones, Dorothy Lamour.
Bank robbers feign a medical emergency and kill a financier; with Elizabeth Allen, Edgar Bergen; Dick Clark.
An international playboy resembling Amos is shot at close range.
Charred $1000 bills from a poker game surround the body of a wealthy man in his hotel suite; guests Tammy Grimes, Burgess Meredith.
Loose bolts on a diving board suggest foul play in a woman's death; guests June Allyson, Yvonne De Carlo, Agnes Moorehead.
A model/photographer is found dead in a mock-up of an electric chair; guests Nick Adams, Terry Moore, Elsa Lanchester.
Amos tries to locate an oil millionaire, whose ex-wife has been slain; guests Frankie Avalon, Macdonald Carey, Una Merkel.
A sorceress sends Burke a message that lists the suspects in his upcoming murder; guests Wally Cox, Telly Savalas, Gloria Swanson.
While on the phone, asking Burke for protection, a society psychologist is shot; with Annette Funicello, James MacArthur.
A shipbuilder is on his plane when it explodes, but he actually dies from a morphine overdose; guests Anne Francis, Nancy Sinatra.
Burke suspects an agent, a music arranger and an astrologer in the death of a recording star.
The remaining three siblings are suspect in the death of a quadruplet; guests Richard Carlson, Carolyn Jones, Michael Wilding.
A publisher is stabbed to death at the opening of his new nightclub; guests Arlene Dahl, Sammy Davis Jr., Diana Dors, Suzy Parker.
No clues are found in the strangulation of a novelist; guests Rita Moreno, Terry-Thomas.
Someone tampers with a wealthy promoter's car, causing a fatal crash; guests Lola Albright, Joan Blondell, Barbara Eden, Eva Gabor.
A big-game hunter is shot with one of his own guns; with Mary Astor, Zsa Zsa Gabor, Paul Lynde, John Saxon, Chill Wills.
A tycoon is found with a bullet in his back, next to a merry-go-round; guests Jim Backus, Barrie Chase, Dina Merrill, Soupy Sales.
A model is found drowned at an estate owned by three wealthy Texans; guests William Bendix, Suzy Parker, ZaSu Pitts, Will Rogers Jr.